Eight different itineraries on seven ships offered by five cruise lines: September may be on the late-ish side of the Mediterranean cruise season, but opportunities abound for autumnal voyages. Norwegian’s Epic is based in Barcelona throughout the summer while Celebrity’s Beyond and Constellation will be making 8- and 9-night cruises to the western Mediterranean in September.
| Norwegian Epic | September 4, 2022 September 11, 2022 September 18, 2022 September 25, 2022 | 7 nights | Weekly cruises to the western Mediterranean |
| Celebrity Beyond | September 15, 2022 September 24, 2022 | 9 nights | To France and the Italian Riviera |
| Celebrity Constellation | September 25, 2022 | 8 nights | Best of the western Mediterranean |
Royal Caribbean will be sending both Vision of the Seas and Wonder of the Seas out from Barcelona to explore the Mediterranean in September:
| Royal Caribbean Vision of the Seas | September 2, 2022 September 15, 2022 September 23, 2022 | 8 nights | Sete, Provence, Corsica, Sardinia, Palma de Mallorca, Cartagena, Valencia |
| Royal Caribbean Vision of the Seas | September 10, 2022 | 5 nights | Nice, Rome, Florence, Provence |
| Royal Caribbean Wonder of the Seas | September 4, 2022 September 11, 2022 September 18, 2022 September 25, 2022 | 7 nights | Palma de Mallorca, Provence, Florence, Civitavecchia (Rome), Naples |
Regal Princess ventures forth on the most extensive cruise (or maybe we should say “cruises”) from Barcelona in September, with 7, 14 and 21 day options that may take you as far as Istanbul. Holland America’s Oosterdam also makes a longer cruise in September, from Barcelona to Venice.
| Regal Princess | September 3, 2022 September 24, 2022 | 7 or14 or 21 nights | Gibraltar, Marseille, Genoa, Florence, 7 day cruise ends in Rome, 14-day continues to Greece, Turkey, 21 day returns to Barcelona |
| Holland America Oosterdam | September 16, 2022 | 12 nights | Marseille, Villefranche, Livorno, Civitavecchia, Naples, Corfu, Dubrovnik, Montenegro, ends in Venice |